Topographic Single Nucleotide Polymorphism

This project is supported by NIH grant CA204962.
Please cite this paper if you publish or present results using TopoSNP analysis:
  • Stitziel N O, Binkowski T A, Tseng Y Y, Kasif S, Liang J. 2004. topoSNP: a topographic database of non‐synonymous single nucleotide polymorphisms with and without known disease association. Nucleic Acids Research. 32(suppl_1), D520-D522.
  • Entry for COSMIC Cancer Variant

    Select the Data Source for Querying

    Examples of querying TopoSNP
    HGNC Gene Symbol ALAD
    Uniprot P13716
    NCBI Protein Accession Number NP_000022.3
    PDB 5HMS
    dbSNP rs121912984

    Statistics for Current TopoSNP Release
    dbSNP Release B151 (GRCh38p13)
    OMIM Release Dec 20 2017

    HGNC Gene Symbol Entries 2,614
    Uniprot Entries (Redundant, including Swissport/Reviewed and TrEMBL/Unreviewed) 4,453
    NCBI Protein Accession Entries (Isoforms/Alternative Splicing) 5,762
    PDB Chain Entries 8,821
    dbSNP Entries 182,313